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eRAM

encyclopedia of Rare Disease Annotation for Precision Medicine




Disease cone rod dystrophy
Comorbidity C0341747|detrusor sphincter dyssynergia
Sentences 2
PubMedID- 22977301 Btx-a in the urinary tract was first described by dykstra et al in 1988, who injected it into the external urinary sphincter to treat detrusor sphincter dyssynergia in patients with spinal cord injury.24 subsequently, schurch et al reported its use in the treatment of neurogenic detrusor overactivity in 12 patients with spinal cord injury.25 its use has since expanded in the management of lower urinary tract symptoms associated with idiopathic detrusor overactivity,26 bladder outflow obstruction,27 and painful bladder syndrome/interstitial cystitis.
PubMedID- 25042140 Following use of botulinum toxin in the 1980s for the treatment of detrusor sphincter dyssynergia in patients with spinal cord injury (sci), the potential therapeutic value of this neurotoxin in urology has been the subject of much interest.

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